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Medical Equipment & Supplies

S100A8

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008] http://www.creativebiomart.net/symbolsearch_S100A8.htm (Ad#: f5080-1010)

Web Site: http://www.creativebiomart.net/symbolsearch_S100A8.htm
E-mail: contact@creative-biomart.com

Retn

This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] http://www.creativebiomart.net/symbolsearch_Retn.htm (Ad#: f5080-1012)

Web Site: http://www.creativebiomart.net/symbolsearch_Retn.htm
E-mail: contact@creative-biomart.com

RAD51

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] http://www.creativebiomart.net/symbolsearch_RAD51.htm (Ad#: f5080-1014)

Web Site: http://http://www.creativebiomart.net/symbolsearch_RAD51.htm
E-mail: contact@creative-biomart.com

affinity maturation of antibodies

Creative Biolabs has gained extensive experience in antibody affinity maturation. We usually take scFv as the antibody format in affinity maturation. Also, a monovalent display phagemid system is used to reduce the avidity effects during antigen-binding screening. We also provide affinity maturation services for single domain antibodies. Two methods, untargeted mutagenesis and oligonucleotide-directed mutagenesis, are employed to construct random or defined sub-libraries to introduce a large number of mutants of the original antibody. Antibody binders of higher affinity are then selected by increasing the screening stringency. By constructing a series of sub-libraries of a scFv/Fab antibody, our proprietary protocol allows increase of the affinity of the scFv antibodies from 10 -9 to 10 -10. We have successfully obtained a scFv antibody that has an extremely high affinity of 10 -12, whose binding to the antigen is essentially irreversible. (Ad#: f5080-1016)

Web Site: http://www.creative-biolabs.com/antibody-affinity-maturation.html
E-mail: candyjkswift@gmail.com

affinity maturation

Affinity maturation is the process to improve antibody affinity for an antigen. In vivo, natural affinity maturation by the immune system takes place by somatic hypermutation and clonal selection. In vitro, in the laboratory affinity maturation, can be obtained by mutation and selection. Creative Biolabs has gained extensive experience in antibody affinity maturation. We usually take scFv as the antibody format in affinity maturation. Also, a monovalent display phagemid system is used to reduce the avidity effects during antigen-binding screening. We also provide affinity maturation services for single domain antibodies. Two methods, untargeted mutagenesis and oligonucleotide-directed mutagenesis, are employed to construct random or defined sub-libraries to introduce a large number of mutants of the original antibody. (Ad#: f5080-1018)

Web Site: http://www.creative-biolabs.com/antibody-affinity-maturation.html
E-mail: candyjkswift@gmail.com

Georgia Medical Transportation

We are the most trusted organization which provides non emergency medical transportation in Georgia. We also provide non emergency wheelchair transportation as well as stretcher transportation services. For more details Visit our website: http://www.atm-ga.com (Ad#: f5080-1020)

Web Site: http://www.atm-ga.com
E-mail: atmga00@gmail.com

Purchase MTP KIT Online Medicine

MTP KIT means Medical Termination of Pregnancies, this medicine used to stop unwanted pregnancy. This medicine available on online at cheapest prise with free shipping.Most benifit of MTP Kit is that they're more cost-effective compared to the surgical operation. http://www.goabortion.com/mtp-kit.html (Ad#: f5080-1022)

Web Site: http://www.goabortion.com/
E-mail: steven.watson756@gmail.com

single domain antibody

Creative Biolabs is a well-recognized leader in single domain antibody (sdAb) library construction and screening services. Our unique services including: Construction of immunized sdAb library (camel, llama, alpaca or even shark repertoire) Construction of synthetic sdAb library (naïve or camelized human repertoire) Screening of single domain antibody libraries Large-scale production of recombinant sdAb http://www.creative-biolabs.com/single-domain-antibody-library-service.html (Ad#: f5080-1024)

Web Site: http://www.creative-biolabs.com/single-domain-antibody-library-service.html
E-mail: candyjkswift@gmail.com

antibody libraries

HuScL-1(R), HuScL-2(R), HuScL-3(R) and HuScL-4(R) Human Single Chain (scFv) Antibody Libraries are natural or synthetic libraries of a diversity of over 2.0×109. Recently, we have created a next-generation, fully-human, yeast display scFv library - HuScL-YDP. We also have a HuFabL(R) Human Fab Antibody Library of a size of 2.0×109. Besides human antibody libraries, we have a MuScL(R) Murine Single Chain Antibody Library and a MuFabL(R) Murine Fab Antibody Library. (Ad#: f5080-1026)

Web Site: http://www.creative-biolabs.com/premade-human-and-mouse-antibody-libraries.html
E-mail: candyjkswift@gmail.com

anti human antibodies

Creative Biolabs has developed the Fully Human Antibody Technology™ (FHAT) to produce fully human monoclonal antibodies in mice. As a leading custom service provider in human antibody production field, Creative Biolabs has in-licensed two strains of "humanized" transgenic mice (FHAT mice) and successfully demonstrated their applications in discovery and production of unique fully human antibodies against various targets. (Ad#: f5080-1028)

Web Site: http://www.creative-biolabs.com/Human-Antibody-Production-from-Transgenic-Mice.html
E-mail: candyjkswift@gmail.com

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